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6.
An. med. interna (Madr., 1983) ; 23(11): 519-524, nov. 2006. ilus, tab
Artigo em Es | IBECS | ID: ibc-051700

RESUMO

Fundamento y objetivo: Con el aumento de la esperanza de vida en pacientes con infección por el virus de la inmunodeficiencia humana (VIH) tras el tratamiento antirretroviral de gran actividad (TARGA), las causas de hospitalización han cambiado. Predominan ahora comorbilidades como la hepatopatía crónica, la patología cardiovascular o los efectos secundarios de los tratamientos. Nuestro objetivo es determinar las características clinicoepidemiológicas actuales de estos pacientes. Material y métodos: Estudio descriptivo y retrospectivo. Revisamos las historias clínicas de los ingresos de pacientes con infección por el VIH hospitalizados en los servicios médicos de nuestro hospital en el transcurso de un año. Resultados: Hubo 125 ingresos de 82 pacientes, un 77% varones y un 71% con infección por el virus de la hepatitis C (VHC). La edad media fue de 42 años. En el 64% la vía de transmisión fue la drogadicción parenteral. Un 36% recibían TARGA y un 51% reunían criterios sida. Los motivos de ingreso más frecuentes fueron la patologia respiratoria (32%) y las enfermedades definitorias de sida (EDS) con un 22%, de las que la tuberculosis (TBC) fue la más frecuente. Un 10% fueron ingresados en la Unidad de Cuidados Intensivos (UCI). La mortalidad fue del 11% pacientes/año. Conclusiones: La mayoría de los pacientes fueron varones, con coinfección por el VHC y usuarios de drogas vía parenteral, siendo las causas de ingreso más frecuentes las patologías respiratorias y las enfermedades oportunistas. La TBC permanece siendo la EDS más frecuente


Background and objetive: With the increasing life expectancy in human immunodeficiency virus (HIV) infected patients since the highly active antiretroviral therapy (HAART), other underlying comorbilities such as chronic liver patology, cardiovascular diseases or side effects of treatment may lead to hospitalization. The purpose of this study is to determine the clinical and epidemiological characteristics of these patients. Material and methods: A descriptive-retrospective study. We reviewed the clinical records of patients with HIV infection admitted in our medical departments through a year. Results: There were 125 hospitalizations of 82 patients. 77% were males and 71% had hepatitis C virus (HCV) infection. The median age was 42 years. 64% HIV infection had been acquired by sharing material for intravenous drug use. A 36% were receiving HAART and 51% had AIDS. The respiratory tract patology (32%) and AIDS-defining illnesses (22%) were the most frequent causes of hospitalization, and the main opportunistic disease was tuberculosis (TBC). Ten per cent were admitted in the Intensive Care Unit. Mortality rate was 11% patients/year. Conclusions: Most of the patients were male, drug users and HCV positive, and the admissions to hospital were mostly due to respiratory patology and opportunistic diseases. TBC remains like the most frequent AIDS-defining illness


Assuntos
Masculino , Feminino , Adulto , Humanos , Inquéritos de Morbidade , Hepatopatias/complicações , Infecções por HIV/epidemiologia , Infecções por HIV/mortalidade , Comorbidade , Infecções Oportunistas/complicações , Infecções Oportunistas/epidemiologia , Hepatopatias/epidemiologia , Hepatopatias/mortalidade , Estudos Retrospectivos , Doenças Respiratórias/complicações , Doenças Respiratórias/epidemiologia , Doenças Respiratórias/mortalidade , Síndrome de Imunodeficiência Adquirida/epidemiologia , Síndrome de Imunodeficiência Adquirida/mortalidade , Isquemia Miocárdica/complicações , Isquemia Miocárdica/epidemiologia
9.
An Med Interna ; 23(11): 519-24, 2006 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-17222066

RESUMO

BACKGROUND AND OBJECTIVE: With the increasing life expectancy in human immunodeficiency virus (HIV) infected patients since the highly active antiretroviral therapy (HAART), other underlying comorbilities such as chronic liver pathology, cardiovascular diseases or side effects of treatment may lead to hospitalization. The purpose of this study is to determine the clinical and epidemiological characteristics of these patients. MATERIAL AND METHODS: A descriptive-retrospective study. We reviewed the clinical records of patients with HIV infection admitted in our medical departments through a year. RESULTS: There were 125 hospitalizations of 82 patients. 77% were males and 71% had hepatitis C virus (HCV) infection. The median age was 42 years. 64% HIV infection had been acquired by sharing material for intravenous drug use. A 36% were receiving HAART and 51% had AIDS. The respiratory tract pathology (32%) and AIDS-defining illnesses (22%) were the most frequent causes of hospitalization, and the main opportunistic disease was tuberculosis (TBC). Ten per cent were admitted in the Intensive Care Unit. Mortality rate was 11% patients/year. CONCLUSIONS: Most of the patients were male, drug users and HCV positive, and the admissions to hospital were mostly due to respiratory patology and opportunistic diseases. TBC remains like the most frequent AIDS-defining illness.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Infecções por HIV/epidemiologia , HIV-1 , Adulto , Antirretrovirais/uso terapêutico , Causas de Morte , Feminino , Infecções por HIV/tratamento farmacológico , Mortalidade Hospitalar , Humanos , Pacientes Internados/estatística & dados numéricos , Masculino , Morbidade , Estudos Retrospectivos , Espanha/epidemiologia
15.
An Med Interna ; 21(2): 75-8, 2004 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-14974893

RESUMO

Listeria monocytogenes is still a very rare opportunist infection in immunosuppressive patients. The clinical-epidemiological and therapeutic characteristics in 10 patients with infection produced by LM are reported--four of them had primary bacteriemia, three patients had a meningeal involvement, there were two patients with spontaneous bacterial peritonitis and one suffered from abdominal access. All of the patients had underlying disorders favouring the infection. Sepsis and meningeal syndrome were the most common presenting forms. Ampicillin was the most used antibiotic. The overall mortality was 40%.


Assuntos
Abscesso Abdominal/microbiologia , Bacteriemia/microbiologia , Listeria monocytogenes/isolamento & purificação , Listeriose/microbiologia , Peritonite/microbiologia , Abscesso Abdominal/tratamento farmacológico , Abscesso Abdominal/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Bacteriemia/tratamento farmacológico , Bacteriemia/epidemiologia , Feminino , Humanos , Hospedeiro Imunocomprometido , Listeriose/tratamento farmacológico , Listeriose/epidemiologia , Masculino , Meningite por Listeria/tratamento farmacológico , Meningite por Listeria/epidemiologia , Meningite por Listeria/microbiologia , Pessoa de Meia-Idade , Peritonite/tratamento farmacológico , Peritonite/epidemiologia , Resultado do Tratamento
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